To Evaluate The Pervasiveness of Candida Infection Which Constitute An Opportunistic Infection Predominantly In Immunocompromised Patients.

  Himanshu Singh Bisht,  Sunpreet kaur,  Aishwarya Srivastava,  Shruti Sharma

Candida is a yeast like fungus causing commonest fungal infections. Candida is normal inhabitant in the skin, mucous membrane of oral cavity including gastrointestinal tract, respiratory tract and genitourinary tract and may invade other parts of the body especially in immunocompromised individuals. Aim of the study was to determine the prevalence of candida infection and its prevalence factor mainly in immunocompromised patient in tertiary care hospital. Materials and Methods: Study will be conducted in the Department Of Microbiology, School of Medical Sciences & Research, Sharda Hospital, Greater Noida. Study type prospective analytical study, sample size 100 sample, specimen oral swabs, ear swabs, vaginal swabs, stool, urine, CSF, sputum, blood, pus, nail scrapings etc. Samples will be collected and processed as per the Standard microbiological procedures. Result: Total 120 isolates of Candida species isolate from various clinical specimens speciated and antifungal susceptibility was found. The prevalence of Candida albicans and non albicans candida are studied in relation to age, sex, site of isolation , underlying conditions and predisposing factors. Conclusion: Candidiasis is becoming one of the more frequently encountered fungal diseases. The incidence of disease is found to be increased due to predisposing factors like pregnancy, HIV infection, Diabetes etc. Discussion: Candida is yeast like fungus and is a normal commensal of skin and mucous membrane. Candida with change in external and internal environment causes candidiasis. The disease may be mild to severe, superficial to deep, acute to chronic. The origin of disease is commonly endogenous and represent an opportunistic infection mainly in immunocompromised patients and exogenous source is nosocomial in origin.

Keywords- Candida, Candidiasis, Non- albicans, Fungal Infection, Immunocompromised patient

Unique Identification Number - IJEDR2004025
Page Number(s) - 142-146
Pubished in - Volume 8 | Issue 4 | December 2020
DOI (Digital Object Identifier) -   
Publisher - IJEDR (ISSN - 2321-9939)

  Himanshu Singh Bisht,  Sunpreet kaur,  Aishwarya Srivastava,  Shruti Sharma,   "To Evaluate The Pervasiveness of Candida Infection Which Constitute An Opportunistic Infection Predominantly In Immunocompromised Patients.", International Journal of Engineering Development and Research (IJEDR), ISSN:2321-9939, Volume.8, Issue 4, pp.142-146, December 2020, Available at :http://www.ijedr.org/papers/IJEDR2004025.pdf