Studies to explore the impact of Carbon & Nitrogen source for Lincomycin production at shake flask level using  Streptomyces lincolnensis

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Paper Details

Paper Title

Studies to explore the impact of Carbon & Nitrogen source for Lincomycin production at shake flask level using Streptomyces lincolnensis

Authors

Aditi Trivedi, Dr.Umesh Luthra, Nishtha Singh, Vrushali Bagwe, Mitali Lade

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Abstract

Lincomycin and its derivatives are antibiotics exhibiting biological activity against Gram-positive bacteria. The semisynthetic chlorinated lincomycin is used in the clinal practices. The importance of carbon and nitrogen sources and the ideal carbon and nitrogen sources were optimized. Different phosphates were studied and their concentration was optimized. The concentration of dextrose, soya flour and sodium nitrate was determined using full factorial design. ANOVA analysis showed that dextrose and soya flour were significant components which had a greater impact on yield. The overall yield of lincomycin was increased from 1g/l to 3.5 g/l.

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Publication Details

Unique Identification Number - IJEDR1901049
Page Number(s) - 270-276
Pubished in - Volume 7 | Issue 1 | February 2019
DOI (Digital Object Identifier) -
Publisher - IJEDR (ISSN - 2321-9939)

Cite this Article

Aditi Trivedi, Dr.Umesh Luthra, Nishtha Singh, Vrushali Bagwe, Mitali Lade, "Studies to explore the impact of Carbon & Nitrogen source for Lincomycin production at shake flask level using Streptomyces lincolnensis", International Journal of Engineering Development and Research (IJEDR), ISSN:2321-9939, Volume.7, Issue 1, pp.270-276, February 2019, Available at :http://www.ijedr.org/papers/IJEDR1901049.pdf

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