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Paper Details
Paper Title
Simulation and Analysis of Microcantilever Sensor for enhanced Biosensing of Disease causing pathogens
Authors
P.Sangeetha, Dr.A.Vimala Juliet
Abstract
This paper deals with a biosensor using a micro fabricated array of micromechanical cantilevers. This biosensor is used to detect tuberculosis. The sensor consists of antibody layer immobilized onto gold-coated cantilevers and interacts with antigen. The patient blood sample is placed on the cantilever surface. If the sample contains disease causing antigen, immobilized antibody binds with the antigen. This antigen antibody binding causes increase in surface stress. The addition of mass due to antigen antibody binding involved in this process causes the cantilever to bend. The deflection of these cantilever beams can be detected using various techniques like piezoresistive, piezoelectric or capacitive effects. The detection of pathogens requires an extremely sensitive cantilever. Increasing the sensitivity of a microcantilever biosensor can be done by changing the shape of the cantilever. Intellisuit software is used to analyze the proposed microcantilever with increased sensitivity.
Keywords- Biosensor, antibodies,Cantilever.
Publication Details
Unique Identification Number - IJEDRCP1403027Page Number(s) - 131-136Pubished in - Volume 2 | Issue NCETSE Conference | March 2014DOI (Digital Object Identifier) - Publisher - IJEDR (ISSN - 2321-9939)
Cite this Article
P.Sangeetha, Dr.A.Vimala Juliet, "Simulation and Analysis of Microcantilever Sensor for enhanced Biosensing of Disease causing pathogens", International Journal of Engineering Development and Research (IJEDR), ISSN:2321-9939, Volume.2, Issue NCETSE Conference, pp.131-136, March 2014, Available at :http://www.ijedr.org/papers/IJEDRCP1403027.pdf
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