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Paper Details
Paper Title
Evaluation of antimicrobial activity of cuminum cyminum & piper nigrum seed extract against isolated urinary pathogens
Authors
  Sharmila Donepudi,  U. Mahalakshmi,  M. Chandana,  R. Soniya, Mounika Sai,  T. Saileela
Abstract
Urinary tract infection (UTI) is one of the most widely recognized bacterial disease in everybody all through the world. with growing concern about the greater occurrence of antibiotic resistance among bacteria and particularly uropathogens, many efforts were done to find effective agents. Cuminum cyminum L. (cumin) and Piper nigrum L. (black pepper) were reported with good antimicrobial activity. This study evaluated the activity of selected herb extract in combination against isolated uropathogens from 50 urine sample of patients suffering from Urinary tract infection. After isolation and screening of organism, susceptibility testing was carried out by disc diffusion method and minimum inhibitory concentration values by broth dilution testing. The activity was assessed by comparing alcoholic extract of selected herbs with standard drugs like Ciprofloxacin, Gentamicin and ampicillin common drugs used in UTI. Based on the results obtained it was made clear that both Cumin and Pepper extract exhibited suitable inhibition against urinary pathogens and in combination they exhibited improved activity. The MIC value of cumin extract against isolated urinary pathogens was determined by broth dilution method.
Keywords- Urinary tract infection, Cuminum cyminum L., Piper nigrum L., Disc diffusion method, Mininmum Inhibitory concentration
Publication Details
Unique Identification Number - IJEDR2002065Page Number(s) - 389-392Pubished in - Volume 8 | Issue 2 | April 2020DOI (Digital Object Identifier) -    Publisher - IJEDR (ISSN - 2321-9939)
Cite this Article
  Sharmila Donepudi,  U. Mahalakshmi,  M. Chandana,  R. Soniya, Mounika Sai,  T. Saileela,   "Evaluation of antimicrobial activity of cuminum cyminum & piper nigrum seed extract against isolated urinary pathogens", International Journal of Engineering Development and Research (IJEDR), ISSN:2321-9939, Volume.8, Issue 2, pp.389-392, April 2020, Available at :http://www.ijedr.org/papers/IJEDR2002065.pdf
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